They found that people with type O blood had a lower risk for contracting the coronavirus (SARS-CoV-2) compared to those with type A, B or AB. Other possible explanations involve blood group antigens and how they affect the production of infection fighting antibodies. They found that blood group wasn't a risk factor for hospitalization or death from Covid-19. The retrospective study found that there were more people with blood type A, B, and AB who tested positive than type O. When these antigens come into contact with a pathogen or other unfamiliar substance, they trigger an immune system response. They compared the ABO blood group distribution in 2173 patients with COVID-19 from 3 hospitals in Wuhan and Shenzhen, China, with that in the general population in those regions. You will be asked to register or log in. The results of the present study suggest that while the blood group A might have a role in increased susceptibility to the COVID-19 infection, the blood group O might be somewhat protective. The results were notable: Adjusting for demographics and co-morbidities, the risk for a COVID-19 diagnosis was 12 percent lower for people with type O blood and the risk for severe COVID-19 or death was 13 percent lower, compared to those with A, AB, or B blood types. Once you confirm that subscription, you will regularly And several other peer-reviewed studies reinforce these findings. These new findings—the first to identify statistically significant susceptibility genes for the severity of COVID-19—come from a large research effort led by Andre Franke, a scientist at Christian-Albrecht-University, Kiel, Germany, along with Tom Karlsen, Oslo … “Clotting is always a good thing if you cut yourself, but it's a bad thing, generally, if you get a really bad infection [because it] activates the clotting cascade and tends to activate clotting in small blood vessels,” he says. "I think this has scientific interest, and when we find out what the mechanism is, perhaps we're able to use that proactively in some way in regard to treatment.". Get instant access to discounts, programs, services, and the information you need to benefit every area of your life. You must be logged in to leave a comment. Please enable Javascript in your browser and try (CNN)People with blood type O may be less vulnerable to Covid-19 and have a reduced likelihood of getting severely ill, according to two studies published Wednesday. En español | In the last several months, a number of studies have drawn a connection between blood type and COVID-19 risk, and most have reached the same conclusion: People with type O blood, the most common kind, may have a slight advantage over their peers when it comes to risk for a coronavirus infection and hospitalization or death from COVID-19. Blood type is not associated with a severe worsening of symptoms in people who have tested positive for COVID-19, report Harvard Medical School researchers based at Massachusetts General Hospital. A genetic analysis of COVID-19 patients suggests that blood type might … It's unlikely that doctors will make treatment decisions based on blood type, Silverstein says, and he cautions that blood type should not be considered on the same level of risk as age, obesity or other underlying health conditions. The provider’s terms, conditions and policies apply. "It's a repeated, interesting scientific observation that really warrants further mechanistic work," he said. Please return to AARP.org to learn more about other benefits. One explanation: Your blood type is based on proteins, called antigens, that cover the surface of your red blood cells. And if you're blood group O, you're not free to go to the pubs and bars.". Experts say more research is needed. The Canadian study also found those with blood type A or AB had a longer stay in the intensive care unit, a median of 13.5 days, compared with those with blood group O or B, who had a median of nine days. "We're starting to see enough now that I think it's an important research question to answer," he said. Most humans fall into one of four blood groups: A, B, AB or O. Even still, experts caution that the accumulating evidence on this subject shouldn't influence everyday medical or public health decisions. In contrast, people with blood type O appear to have about a 50 percent reduced risk of severe COVID-19. AARP is a nonprofit, nonpartisan organization that empowers people to choose how they live as they age. You can also manage your communication preferences by updating your account at anytime. In the meantime, please feel free "We do not know whether this is some kind of protection of group O, or whether it's some kind of vulnerability in the other blood groups," he said. They found that people with Type A blood had a 21% greater risk of the disease than their counterparts with other blood types, and that people with Type O blood had a 33% lower risk. Despite the growing body of research suggesting some link between COVID-19 and blood type, experts say these studies don't change much for the individual. And a complication seen in many people with severe COVID-19 is blood clots in the small blood vessels of the lungs. Deaths among this population were 12 times as high. People with blood type O may have lower risk of COVID-19 infection and severe illness, two new studies suggest. Additionally, people with Rh-negative blood were found to have a lower probability of both infection and serious COVID-19 illness than people with Rh-positive blood. Updated 2029 GMT (0429 HKT) October 14, 2020. People with blood type O may be less vulnerable to Covid-19 and have a reduced likelihood of getting severely ill, according to two studies published Wednesday. Canadian researchers reached a similar finding in their retrospective study published in Annals of Internal Medicine. Still, the larger study did find that Type O blood was between 9 and 18 percent less likely to test positive for COVID-19 when compared to the other blood types… In the next 24 hours, you will receive an email to confirm your subscription to receive emails Researchers in Denmark found that among more than 7,400 people who tested positive for COVID-19, fewer individuals had type O blood compared to type A, despite the fact that the two blood types accounted for the same share of the population when compared to a larger control group. (Patrick T. Fallon/Bloomberg/Getty Images/CNN) But in terms of a definitive marker we need repeated findings across many jurisdictions that show the same thing," said Dr. Mypinder Sekhon, an intensive care physician at Vancouver General Hospital and an author of the Canadian study. This, however, does not mean they can't contract the virus or fall seriously ill from it. Research has shown that people with type O blood are more likely to get seriously ill from cholera than others who come down with the illness; and type O blood has been shown to offer some protection against severe malaria. A June report from the Centers for Disease Control and Prevention (CDC) found that hospitalizations for people with COVID-19 were six times as high for patients with chronic health conditions like heart disease, lung disease and diabetes, compared to otherwise healthy individuals. Sometimes called COVID toe, the rash resembles frostbite. Blood type may also influence norovirus susceptibility. By contrast, 44.4% of group A tested positive, while in the wider Danish population that blood type makes up 42.4%. A Danish study found that among 7,422 people who tested positive for Covid-19, only 38.4% were blood type O -- even though, among a group of 2.2 million people who were not tested, that blood type made up 41.7% of the population. However, once infected, blood group type does not seem to influence clinical outcome. “They are at risk for COVID, just a little bit lower than type A.… That doesn't mean that [type] O is zero risk.”. AARP members receive exclusive member benefits & affect social change. The researchers found that type O blood was associated with a lower risk for COVID-19, while type A blood was associated with a higher risk. That previous genetic study, paired with the two new studies in Blood Advances, are "suggestive that this is a real phenomenon that we're seeing," said Adalja, whose work is focused on emerging infectious disease. Nor should people worry unduly about the link between blood type and Covid-19, said Dr. Torben Barington, the senior author of the Danish paper and a clinical professor at Odense University Hospital and the University of Southern Denmark. What is emergency use authorization for COVID-19 vaccines and treatments, Trial data shows coronavirus vaccines are highly effective, Keep Sharp: Build a Better Brain at Any Age Book. www.aarp.org/volunteer. again. More specific to the coronavirus is the theory of clotting. Why do we have different blood types — and do they make us more vulnerable to Covid-19? Type O is associated with lower risk compared with all the other blood groups. Here's how to find out yours, The New England Journal of Medicine in June. People with certain blood types could be at an increased risk of dying from coronavirus, experts warn Credit: Getty Images - Getty. In the other study, researchers in Canada found that among 95 patients critically ill with Covid-19, a higher proportion with blood type A or AB -- 84% -- required mechanical ventilation compared with patients with blood group O or B, which was 61%. Both studies were published in the journal Blood Advances. "If one is blood group A, you don't need to start panicking. As for the novel coronavirus that causes Covid-19, "We need to figure out the mechanism and understand it at the molecular level to be able to say for sure how this is occurring -- that this is really the O blood type and not something that kind of tracks with O blood type," Adalja said. What's more, 95 percent of COVID-19 deaths in the U.S. have occurred in adults 50 and older. 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The research provides further evidence that blood type (also known as blood group) may play a role in a person's susceptibility to infection and their chance of having a severe bout of the disease. It makes very little difference to most people's daily lives unless you have to have a blood transfusion. Visit today. Small blood clots can become lodged in tiny blood vessels. "As a clinician ... it is at the back of my mind when I look at patients and stratify them. “There's a fairly decent amount of existing literature beyond SARS-CoV-2” that certain blood types can play a role in disease risk and severity, says Joel Ray, M.D., a clinician scientist and professor at St. Michael's Hospital in Toronto and lead author of the study published in Annals of Internal Medicine. The researchers found that people with blood type O had a lower chance of severe COVID illness or death compared to people with other blood types. People with type A blood seem to be at higher risk for severe COVID-19, while those with type O blood appear to be less likely to test positive for COVID … "There's more science to be done here, but it seems to me that there's more evidence accumulating for this hypothesis. According to their data, those with O blood type are between 9-18% percent less likely than individuals with other blood types to have tested positive for COVID-19. Sign up here to get The Results Are In with Dr. Sanjay Gupta every Tuesday from the CNN Health team. The blood type–infection connection is not unique to the coronavirus. Their findings, published in the Annals of Hematology , dispel previous reports that suggested a correlation between certain blood types and COVID-19. "While we're not quite to the point where this is ironclad, it's clearly suggestive, and we have not seen anything inconsistent with this. The local blood testing lab has seen increased demand from people asking if their blood type puts them at risk of COVID-19. Save 25% when you join AARP and enroll in Automatic Renewal for first year. "There is a precedent in biology for blood type influencing infection,” Silverstein says. receive communications related to AARP volunteering. And though researchers still don't know why or how blood type may interact with SARS-CoV-2, a better understanding could “lead to discovering new pathways or new targets for treatment,” he adds. People with type O blood may be at a lower risk of catching coronavirus and being admitted to hospital by the disease, according to a study from 23andMe, the … You'll start receiving the latest news, benefits, events, and programs related to AARP's mission to empower people to choose how they live as they age. In contrast, people with blood type O appear to have about a 50 percent reduced risk of severe COVID-19. 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